If you live in Windows Hell during your workday, do yourself a favor. Install AutoHotKey. Then create a script and paste this:

;Remaps 'CMD S' to save
!s::
    send !
    sleep, 500
    send f
    sleep, 300
    send s
Return

; Switches left control & alt keys

LCtrl::Alt
LAlt::Ctrl
LWin::LWin

Set that script to load when Windows does. You're welcome.